MYB interacts with androgen receptor, sustains its ligand-independent activation and promotes castration resistance in prostate cancer.
Sanjeev Kumar SrivastavaMohammad Aslam KhanShashi AnandHaseeb ZubairSachin Kumar DeshmukhGirijesh Kumar PatelSeema SinghJoel AndrewsBin WangJames Elliot CarterAjay Pratap SinghPublished in: British journal of cancer (2021)
Our findings reveal a novel MYB-AR crosstalk in PCa and establish its role in castration resistance.