Chronic exposure to PM2.5 aggravates SLE manifestations in lupus-prone mice.

Victor Yuji YariwakeJanaína Iannicelli TorresAmandda Rakell Peixoto Dos SantosSarah Cristina Ferreira FreitasKátia De AngelisSylvia Costa Lima FarhatNiels Olsen Saraiva CâmaraMariana Matera Veras

Published in: Particle and fibre toxicology (2021)

This work shows that air pollution aggravates some SLE manifestations in lupus-prone mice. These results reinforce the need of reducing air pollutant levels in order to promote a better quality of life for individuals diagnosed with SLE.

Keyphrases

systemic lupus erythematosus
disease activity
air pollution
particulate matter
high fat diet induced
rheumatoid arthritis
lung function
wild type
heavy metals
cystic fibrosis
water soluble