Systemic inhibition of 5-lipoxygenase by MK-886 exacerbates apical periodontitis bone loss in a mouse model.

Igor Bassi Ferreira PeteanAlice Corrêa Silva-SousaRaquel Assed Bezerra da SilvaMarília Pacífico LucisanoLéa Assed Bezerra da SilvaGuilherme Piedade Assed de CastroManoel Damião Sousa-NetoLúcia Helena FaccioliFrancisco Wanderley Garcia Paula-Silva

Published in: BMC oral health (2023)

Systemic treatment with MK-886 exacerbated LPS-induced apical periodontitis in a mouse model.

Keyphrases

mouse model
lps induced
bone loss
inflammatory response
combination therapy