Somatic POLE Mutation and Ultra-Hypermutated Genotype in a De Novo High-Grade, Isocitrate Dehydrogenase Wild-Type Glioma: Treatment Implications.
Daniel MundtIsaac Melguizo-GavilanesAnil Y TumuSteven DubnerMary K WaltersLaura McFarlanePublished in: JCO precision oncology (2024)
Pembrolizumab leads to a durable response in ultra-hypermutated, high-grade, glioma.