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Is Laminar Cartilage Composition as Determined by T2 Relaxometry Associated with Incident and Worsening of Cartilage or Bone Marrow Abnormalities?

Frank W RoemerFelix EcksteinGeorg DudaAli GuermaziSusanne MaschekLeena SharmaWolfgang Wirth
Published in: Cartilage (2020)
Contrary to our hypothesis, increased deep layer cartilage T2 was associated with subsequent worsening of cartilage damage, whereas superficial layer T2 was related to subsequent BML worsening. Yet, this relationship was observed in some, but not in all cartilage plates.
Keyphrases
  • extracellular matrix
  • bone marrow
  • cardiovascular disease
  • mesenchymal stem cells
  • oxidative stress