The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: a safety study.

Gansheng TanAnna L HuguenardKara M DonovanPhillip DemarestXiaoxuan LiuZiwei LiMarkus AdamekKory LavineAnanth K VellimanaTerrance T KummerJoshua W OsbunGregory J ZipfelPeter BrunnerEric C Leuthardt

Published in: medRxiv : the preprint server for health sciences (2024)

Our study found that taVNS treatment did not induce adverse cardiovascular effects, such as bradycardia or QT prolongation, supporting its development as a safe immunomodulatory treatment approach for SAH patients. The observed acute increase in heart rate after taVNS treatment may serve as a biomarker for SAH patients who could derive greater benefit from this treatment.

Keyphrases

heart rate
subarachnoid hemorrhage
end stage renal disease
blood pressure
prognostic factors
combination therapy
drug induced
liver failure
smoking cessation
acute respiratory distress syndrome
patient reported
electronic health record
mechanical ventilation