Association between clot composition and stroke origin in mechanical thrombectomy patients: analysis of the Stroke Thromboembolism Registry of Imaging and Pathology.
Brinjikji WRaul G NogueiraPeter KvammeKennith F LaytonJosser E Delgado AlmandozRicardo A HanelVitor Mendes PereiraMohammed A AlmekhlafiAlbert J YooBabak S JahromiMatthew J GounisBiraj PatelMehdi AbbasiSeán FitzgeraldOana Madalina MereutaDaying DaiRamanathan D KadirvelKaren M DoyleLuis SavastanoHarry J CloftDiogo C HaussenAlhamza R R Al-BayatiMahmoud H MohammadenLeonardo PisaniGabriel Martins RodriguesIke C ThackerYasha KayanAlexander CopelanAmin AghaebrahimEric SauvageauAndrew M DemchukParita BhuvaJazba SoomroPouya NazariDonald Robert CantrellAjit S PuriJohn EntwistleEric C PolleyDavid F KallmesPublished in: Journal of neurointerventional surgery (2021)
Our study found statistically significant but clinically insignificant differences between clots of CE and LAA etiologies. Future studies should emphasize molecular, proteomic and immunohistochemical characteristics to determine links between clot composition and etiology.