Persistent post-traumatic headache: a migrainous loop or not? The preclinical evidence.
Silvia BenemeiAlejandro Labastida-RamírezEkaterina AbramovaNicoletta BrunelliEdoardo CaronnaPaola DianaRoman GapeshinMaxi Dana HofackerIlaria MaestriniEnrique Martínez PíasPetr MikulenkaOlga TikhonovaPaolo MartellettiAntoinette MaassenVanDenBrinknull nullPublished in: The journal of headache and pain (2020)
At present, despite its high prevalence, PTH is not entirely understood, and the differential contribution of pathophysiological mechanisms, also observed in other conditions like migraine, has to be clarified. Although facing limitations, animal models are needed to improve understanding of PTH. The knowledge of currently available models is necessary to all researchers who want to investigate PTH and contribute to unravel its mechanisms.
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