A Novel Therapeutic Peptide Blocks SARS-CoV-2 Spike Protein Binding with Host Cell ACE2 Receptor.

Sajjan RajpootTomokazu OhishiAshutosh KumarQiuwei PanSreeparna BanerjeeKam Y J ZhangMirza S Baig

Published in: Drugs in R&D (2021)

Blockage of binding of the SARS-CoV-2 spike protein with ACE2 in the presence of the 13AApi may prevent virus entry into host cells. Therefore, the 13AApi can be utilized as a promising therapeutic agent to combat coronavirus disease 2019.

Keyphrases

sars cov
respiratory syndrome coronavirus
coronavirus disease
binding protein
induced apoptosis
angiotensin converting enzyme
angiotensin ii
protein protein
cell cycle arrest
amino acid
single cell
dna binding
cell therapy
mesenchymal stem cells
cell death
oxidative stress
signaling pathway
bone marrow