Serum neuronal exosomes predict and differentiate Parkinson's disease from atypical parkinsonism.

Cheng JiangFranziska HopfnerAntigoni KatsikoudiRobert HeinCandan CatliSamuel EvettsYongzhi HuangHong WangJohn W RyderGregor KuhlenbaeumerGuenther DeuschlAlessandro PadovaniDaniela BergBarbara BorroniMichele T HuJason J DavisGeorge K Tofaris

Published in: Journal of neurology, neurosurgery, and psychiatry (2020)

Increased α-synuclein egress in serum neuronal exosomes precedes the diagnosis of Parkinson's disease, persists with disease progression and in combination with clusterin predicts and differentiates Parkinson's disease from atypical parkinsonism.

Keyphrases

mesenchymal stem cells
stem cells
parkinson disease
drug induced
cerebral ischemia
blood brain barrier
subarachnoid hemorrhage