Treatment with corticosteroids is associated with an increase in ventricular arrhythmia burden in patients with clinically manifest cardiac sarcoidosis: Insights from implantable cardioverter-defibrillator diagnostics.
Maria C MedorStewart SpencePablo B NeryRob BeanlandsSteven PromislowDaniel JuneauRob de KempAndrew C HaLena RivardLorne GulaDavid H BirniePublished in: Journal of cardiovascular electrophysiology (2020)
This study demonstrated, on average, a threefold increase in daily PVC count in clinically manifest CS patients during treatment with corticosteroids compared to pretreatment. There was also a significant increase in episodes of NSVT. Clinicians and patients with active manifest CS should be aware that corticosteroids are unlikely to lead to a reduction in the burdens of PVC and NSVT.