Altered Sleep Micro-architecture and Cognitive Impairment in Patients With Temporal Lobe Epilepsy.
Alex C BenderAfareen JaleelKyle R PellerinSebastian G MoguilnerRani A SarkisSyndey S CashAlice D LamPublished in: Neurology (2023)
There is a fundamental alteration of sleep micro-architecture in TLE, characterized by a reduction in spindle density and spindle-SO coupling, and these changes may contribute to neurocognitive comorbidity in this disorder.