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Characterization of blood bank and transfusion medicine practices for pregnant individuals with fetuses at risk of hemolytic disease in the United States.

Jeremy W JacobsGarrett S BoothKenneth Jpseph MoiseBrian David AdkinsSara BakhtaryRoss M FasanoRuchika GoelHannah D HintonSadia A LaghariLaura Dilly StephensChristopher A TormeyElizabeth P CroweEvan M BlochElizabeth A Abels
Published in: Transfusion (2024)
There is heterogeneity across US institutions regarding the testing, monitoring, and reporting practices for pregnant individuals with fetuses at risk of HDFN, including the use of antibody titers in screening and monitoring programs, the use of paternal RBC antigen testing and cffDNA, and documentation of fetal antigen results. Standardization of laboratory testing protocols and closer collaboration between the blood bank and transfusion medicine service and the obstetric/maternal-fetal medicine service are needed.
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