Analysis of Archival Sera from Norovirus-Infected Individuals Demonstrates that Cross-Blocking of Emerging Viruses is Genotype-Specific.

Kelsey A Pilewski Lauren A Ford-Siltz Kentaro Tohma Joseph A Kendra Michael Landivar Gabriel I Parra

Published in: The Journal of infectious diseases (2024)

Our data show that infection generates narrow, focused immunity directed towards the infecting genotype. We did detect broad cross-blocking in specific individuals, but these responses could be attributed to diverse, genotype-specific antibodies pre-dating GII.6 infection.

Keyphrases

electronic health record
machine learning
big data
deep learning
artificial intelligence