Trends of INR and Fecal Excretion of Vitamin K During Cholestasis Reversal: Implications in the Treatment of Neonates With Intestinal Failure-Associated Liver Disease.
Duy T DaoLorenzo Anez-BustillosAdam M FinkelsteinPaul D MitchellAlison A O'LoughlinGillian L FellMeredith A BakerAlexis K PotemkinKathleen M GuraMark PuderPublished in: JPEN. Journal of parenteral and enteral nutrition (2019)
Children with IFALD are at risk for vitamin K deficiency during cholestasis reversal. Close monitoring and quantified supplementation of vitamin K may be warranted during this period. However, this should not be guided by INR alone, as it is a poor indicator of vitamin K status.