Phenomenologically distinct psychotomimetic effects of ketamine are associated with cerebral blood flow changes in functionally relevant cerebral foci: a continuous arterial spin labelling study.

Thomas A PollakS De SimoniB BarimaniF O ZelayaJ M StoneM A Mehta

Published in: Psychopharmacology (2015)

Here, we provide evidence for the sensitivity of ASL to the effects of ketamine and the strength of subjective experience, suggesting plausible neural mechanisms for ketamine-induced anhedonia and cognitive disorganisation.

Keyphrases

cerebral blood flow
pain management
high glucose
diabetic rats
subarachnoid hemorrhage
drug induced
room temperature
oxidative stress