IDO1 Activity Predicts Lung Toxicity in Patients with Unresectable Stage III NSCLC and Chemoradiotherapy.
Linfang WuYibo GaoDaquan WangYanhua ChenMingmin QianXin XuTao ZhangNan BiLuhua WangPublished in: Journal of oncology (2023)
High baseline IDO1 activity combined with unfavorable baseline FEV1 was predictive of severe RILT in unresectable stage III NSCLC patients. IDO1 might play a role in the acute inflammatory response. Finding effective interventions to alleviate RILT using IDO inhibitors is warranted in the future.
Keyphrases
- inflammatory response
- locally advanced
- small cell lung cancer
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- ejection fraction
- rectal cancer
- advanced non small cell lung cancer
- prognostic factors
- peritoneal dialysis
- drug induced
- liver metastases
- squamous cell carcinoma
- radiation therapy
- lipopolysaccharide induced
- respiratory failure
- brain metastases
- immune response
- extracorporeal membrane oxygenation
- patient reported
- epidermal growth factor receptor