The Cortisol and ACTH Response to Dex/CRH Testing in Women With and Without Perimenopausal Depression.

Gioia M GuerrieriRivka Ben DorXiaobai LiShau-Ming WeiPedro E MartinezLynnette K NeimanDavid R RubinowPeter J Schmidt

Published in: The Journal of clinical endocrinology and metabolism (2021)

Despite reports of increased stress responsiveness in PMD, we observed no abnormalities of HPA axis activity associated with PMD compared with women without depression. These findings suggest that PMD is not uniformly associated with HPA dysregulation and could reflect underlying pathophysiologic processes that are distinct from women with nonreproductive-related depressions.

Keyphrases

depressive symptoms
sleep quality
polycystic ovary syndrome
postmenopausal women
type diabetes
adipose tissue
adverse drug
pregnant women
skeletal muscle
insulin resistance
heat stress