Maternal serum and fetal cord-blood ischemia-modified albumin concentrations in normal pregnancy and preeclampsia: a systematic review and meta-analysis.
Sheshadri Reddy VarikasuvuPragathi DugginaMrudula VedhantamMunikumar ManneNeelakant VarmaSrinivas NagaramPublished in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2017)
This meta-analysis, the first of its kind showed that the increased serum IMA concentrations were indicative of increased oxidative stress in NP and PE. Measurement of maternal serum IMA and fetal cord-blood IMA concentrations were useful as simple, novel, and inexpensive markers of oxidative stress (OS) status in PE patients. Future large-scale studies are needed to explore IMA in relationship to the disease severity in PE.
Keyphrases
- cord blood
- oxidative stress
- pregnancy outcomes
- systematic review
- end stage renal disease
- ejection fraction
- dna damage
- newly diagnosed
- case control
- chronic kidney disease
- birth weight
- ischemia reperfusion injury
- prognostic factors
- early onset
- pregnant women
- peritoneal dialysis
- patient reported outcomes
- preterm birth
- weight loss
- physical activity
- gestational age