Disruption of Tonic Endocannabinoid Signaling Triggers Cellular, Behavioral and Neuroendocrine Responses Consistent with a Stress Response.
Gavin N PetrieGeorgia BalsevichTamás FüzesiRobert J AukemaWouter P F DrieverMario van der SteltJaideep S BainsMatthew N HillPublished in: British journal of pharmacology (2023)
These data indicate that under resting conditions, constitutive eCB signaling restricts activation of the HPA axis through local regulation of CRH neurons in the PVN.