Magnetic Graphene Oxide Nanocomposites Boosts Craniomaxillofacial Bone Regeneration by Modulating circAars/miR-128-3p/SMAD5 Signaling Axis.

Yi HeLejia ZhangSiyuan HuangYuquan TangYiming LiHongyu LiGuanhui ChenXun ChenXiliu ZhangWei Zhao Fei-Long DengDongsheng Yu

Published in: International journal of nanomedicine (2024)

We found that MGO nanocomposites regulated osteogenic differentiation of BMSCs via the circAars/miR-128-3p/SMAD5 pathway, which provided a feasible and effective strategy for the treatment of craniomaxillofacial bone defects.

Keyphrases

bone regeneration
epithelial mesenchymal transition
transforming growth factor
reduced graphene oxide
carbon nanotubes
signaling pathway
transcription factor
molecularly imprinted
soft tissue
visible light
gold nanoparticles
postmenopausal women
replacement therapy
combination therapy
simultaneous determination