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Intrauterine big toenail imprints: A new cause of congenital skin dimples.

Lucia RestanoMartina ZussinoStefano CambiaghiCarlo Gelmetti
Published in: Pediatric dermatology (2019)
Congenital skin dimples (SD) are small cutaneous depressions that can be noted on any part of the body and may be caused by traumatic, mechanical, metabolic, and genetic factors as well as by exposure to infections or drugs. We describe 3 cases of unrelated healthy newborns displaying SD and discuss as a possible explanation the persistent friction of the big toenail onto the immature skin of the fetus during intrauterine life causing as depression in the skin.
Keyphrases
  • soft tissue
  • wound healing
  • big data
  • spinal cord injury
  • pregnant women
  • depressive symptoms
  • cord blood
  • machine learning
  • genome wide
  • copy number
  • preterm infants
  • deep learning