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Outcome Analysis of Osseous Ingrowth in an Artificially Created Gap Non-union Using the Novel 3D Biodegradable Polycaprolactone Poly-l-Lactide Polymer Scaffold: Insights from an Experimental Study.

Sithardhan RajendranArulkumar NallakumarasamyShyam Kumar SarafAmrita GhoshPralay Maiti
Published in: Indian journal of orthopaedics (2022)
The Polycaprolactone Poly-l-Lactide polymer scaffold is biodegradable in-vivo at a suitable half-life. It has an excellent porous structure, no tissue toxicity, excellent mechanical strength, high osteogenesis potential, and osteoconductivity. Therefore, it can be used as bone graft material in the gap non-union and as a void filler in bone defects.
Keyphrases
  • tissue engineering
  • bone regeneration
  • drug delivery
  • bone mineral density
  • soft tissue
  • bone loss
  • oxidative stress
  • postmenopausal women
  • risk assessment
  • climate change
  • oxide nanoparticles