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Liquid chromatography-tandem mass spectrometry method for mycophenolic acid and its glucuronide determination in saliva samples from children with nephrotic syndrome.

Joanna SobiakMatylda ResztakWeronika SikoraJacek ZachwiejaDanuta Ostalska-Nowicka
Published in: Pharmacological reports : PR (2024)
The evaluated LC-MS/MS method has met the validation requirements for saliva MPA and MPAG determination in children with nephrotic syndrome. Further studies are needed to explore plasma-saliva correlations and assess their potential contribution to MPA monitoring.
Keyphrases
  • liquid chromatography tandem mass spectrometry
  • solid phase extraction
  • young adults
  • simultaneous determination
  • molecularly imprinted
  • ms ms
  • high resolution
  • liquid chromatography
  • risk assessment