Regulation of RIP1-Mediated necroptosis via necrostatin-1 in periodontitis.

Liangyu TanWeicheng ChanJing ZhangJiajia WangZizheng WangJie LiuJiaxin LiXinran LiuMin WangLiang HaoYuan Yue

Published in: Journal of periodontal research (2023)

RIP1-mediated necroptosis plays a role in the pathological process of periodontitis in mice. Nec-1 inhibited necroptosis, alleviated inflammation in periodontal tissue, and reduced bone resorption in periodontitis.

Keyphrases

oxidative stress
bone loss
bone mineral density
metabolic syndrome
type diabetes
skeletal muscle
insulin resistance
postmenopausal women
adipose tissue