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The Contribution of Germline Pathogenic Variants in Breast Cancer Genes to Contralateral Breast Cancer Risk in BRCA1/BRCA2/PALB2 -Negative Women.

Alexey LarionovEleanor FewingsJames RedmanMae GoldgrabenGraeme ClarkJohn BoicePatrick ConcannonJonine BernsteinDavid V Continull The Wecare Study Collaborative GroupMarc Tischkowitz
Published in: Cancers (2023)
-negative women, the aggregated burden of PGVs in breast cancer risk genes was associated with the increased risk of CBC and was inversely proportional to the age at onset.
Keyphrases
  • breast cancer risk
  • genome wide
  • bioinformatics analysis
  • genome wide identification
  • copy number
  • dna repair
  • type diabetes
  • genome wide analysis
  • young adults
  • oxidative stress
  • skeletal muscle
  • dna damage