Wenxin Granules Influence the TGFβ-P38/JNK MAPK Signaling Pathway and Attenuate the Collagen Deposition in the Left Ventricle of Myocardial Infarction Rats.
Ya HuangAi-Ming WuLixia LouDongmei ZhangBo NieYizhou ZhaoKeke LiuMingjing ZhaoHongcai ShangPublished in: Cardiology research and practice (2019)
Wenxin granules can affect the inflammation-related TGFβ-p38/JNK MAPK signaling pathway and change the structural properties of myocardium and scar after MI by attenuated collagen deposition in the left ventricular myocardial tissue to improve cardiac function.
Keyphrases
- signaling pathway
- left ventricular
- pi k akt
- transforming growth factor
- epithelial mesenchymal transition
- induced apoptosis
- wound healing
- mitral valve
- heart failure
- hypertrophic cardiomyopathy
- oxidative stress
- acute myocardial infarction
- cardiac resynchronization therapy
- left atrial
- aortic stenosis
- tissue engineering
- pulmonary hypertension
- pulmonary artery
- cell death
- coronary artery disease
- acute coronary syndrome
- ejection fraction
- aortic valve
- endoplasmic reticulum stress
- drug induced