CYP and SXR gene polymorphisms influence in opposite ways acute rejection rate in pediatric patients with renal transplant.

Stefano TuroloAlberto EdefontiLuciana GhioSara TestaWilliam MorelloGiovanni Montini

Published in: BMC pediatrics (2020)

Genetic analysis of polymorphisms implicated in drug metabolism and tacrolimus trough levels may help to forecast the risk of acute rejection and individualize drug dosage in children undergoing renal transplantation.

Keyphrases

liver failure
drug induced
respiratory failure
aortic dissection
young adults
adverse drug
emergency department
intensive care unit
dna methylation
extracorporeal membrane oxygenation