Could OX40 agonist antibody promote activation of the anti-tumor immune response in gastric cancer?
Mário Rino MartinsRogério L D SantosKleber D N JatahyMarina C D MattaThales P BatistaJosé Iran C JúniorMaria D F S BegnamiLeuridan C TorresPublished in: Journal of surgical oncology (2018)
OX40 as a therapeutic agent has been investigated in many preclinical tumor models. Our findings suggest that of levels of costimulatory in T cells in GC will direct future studies on the role that costimulatory receptors play in the failure of T cell-mediated immunity.