Gene-environment interaction in chronic kidney disease among people with type 2 diabetes from The Malaysian Cohort project: a case-control study.

Norfazilah Ahmad Shamsul Azhar Shah Abdul Halim Abdul Gafor Nor Azian Abdul Murad Mohd Arman Kamaruddin N Abd Jalal N Ismail M R Alias Rahman Jamal

Published in: Diabetic medicine : a journal of the British Diabetic Association (2020)

Our findings suggest that the gene-environment interactions of eNOS rs2070744, PPARGC1A rs8192678, KCNQ1 rs2237895 and KCNQ1 rs2283228 with specific environmental factors could modify the probability for chronic kidney disease.

Keyphrases

chronic kidney disease
copy number
genome wide
quality improvement
genome wide identification
cell proliferation
nitric oxide
pi k akt
signaling pathway