Role of Stem Cells in the Pathogenesis and Malignant Transformation of Oral Submucous Fibrosis.

Suvarna Kizhakkoottu Pratibha Ramani Wanninayake Mudiyanselage Tilakaratne

Published in: Stem cell reviews and reports (2024)

We highlight the potential of mucosal stem cells in the regulation and malignisation of OSMF. However, future large-scale clinical studies will be needed to support whether manipulation of this stem cells at molecular level will be sufficient for the treatment and preventing the malignant transformation of OSMF.

Keyphrases

stem cells
cell therapy
current status
risk assessment
combination therapy
single molecule