Preventive effects of guanosine on intestinal inflammation in 2, 4-dinitrobenzene sulfonic acid (DNBS)-induced colitis in rats.

Maria Grazia ZizzoGaetano CaldaraAnnalisa BellancaDomenico NuzzoMarta Di CarloRosa Serio

Published in: Inflammopharmacology (2018)

In conclusion, guanosine exerts beneficial effects in DNBS-induced colitis in rats, through modulation of colonic inflammation, downregulating of NFκB-mediated signaling.

Keyphrases

oxidative stress
lps induced
pi k akt
cell proliferation