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Novel Cyanopyridine Compounds as KHK Inhibitors for Treating NAFLD, NASH, and Type II Diabetes.

Rachel Mata
Published in: ACS medicinal chemistry letters (2024)
Provided herein are novel cyanopyridine compounds as KHK inhibitors, pharmaceutical compositions, use of such compounds in treating NAFLD, NASH, and type II diabetes, and processes for preparing such compounds.
Keyphrases
  • type diabetes
  • cardiovascular disease
  • glycemic control
  • weight loss