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A Novel Heterozygous Missense Variant (c.667G>T;p.Gly223Cys) in USH1C That Interferes With Cadherin-Related 23 and Harmonin Interaction Causes Autosomal Dominant Nonsyndromic Hearing Loss.

Ju Sun SongAmel BahloulChristine PetitSang Jin KimIl Joon MoonJinhyuk LeeChange Seok Ki
Published in: Annals of laboratory medicine (2020)
A heterozygous variant of USH1C that interferes with the interaction between cdh23 and harmonin causes novel AD-NSHL.
Keyphrases
  • early onset
  • hearing loss
  • intellectual disability
  • cell migration
  • cell adhesion