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Variant-specific discrepancy when quantitating BCR-ABL1 e13a2 and e14a2 transcripts using the Europe Against Cancer qPCR assay.

Lasse KjaerVibe SkovMorten T AndersenAnni AggerholmPhilippe ClairMichal GniotKaren SoebyLene UdbyMikkel H DorffHans HasselbalchNiels Pallisgaard
Published in: European journal of haematology (2019)
Our findings suggest that the EAC qPCR assay may underestimate the e14a2 variant compared to the e13a2 variant.
Keyphrases
  • high throughput
  • tyrosine kinase
  • papillary thyroid
  • chronic myeloid leukemia
  • acute lymphoblastic leukemia
  • squamous cell
  • squamous cell carcinoma
  • lymph node metastasis
  • childhood cancer