Effects of alpha lipoic acid on iron overload, lipid profile and oxidative stress indices in β-thalassemia major patients: A cross-over randomised controlled clinical trial.

Elham Sharifi-ZahabiHadi AbdollahzadSeyed Mostafa NachvakJalal MoloudiMohammad Reza GolpayeganiSahar AsiaeiLaya RezavandZeynab IrajiKhadijeh Jamshidi

Published in: International journal of clinical practice (2021)

The results of this study indicated that supplementation with 600 mg/d ALA may decrease serum ferritin in β-TM. Further studies are needed to confirm the findings.

Keyphrases

clinical trial
oxidative stress
end stage renal disease
ejection fraction
newly diagnosed
study protocol
prognostic factors
peritoneal dialysis
dna damage
ischemia reperfusion injury
patient reported outcomes
phase ii
signaling pathway
double blind
case control