Predictors of gastrointestinal bleeding in patients following left ventricular assist device implantation: a systematic review and meta-analysis.
Manesh Kumar GangwaniMuhammad AzizAli NawrasFnu PriyankaZohaib AhmedRaja Samir KhanMohammad Aadil QamarFawad HaroonAbeer AzizWade Lee SmithShri Jai Kirshan RaviVishal ParikhZakaria AlyousifAsif MahmoodRaseen TariqDevesh RaiWilbert S AronowPublished in: Future cardiology (2022)
Aim: Our study aims to provide a more holistic understanding of the available data and predictive risk factors for gastrointestinal bleed (GIB). Materials & methods: We searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials and Web of Science Core Collection and calculated relative risk and meta-regression was utilized to evaluate for risk factors in order to assess the effect of covariates. Results: Our meta-analysis reported a pooled prevalence rate of GIB of 24.4%. Meta-regression analysis did not yield a statistically significant association between GIB and risk factors, including age, gender, hypertension, chronic kidney disease and diabetes. Conclusion: Studies investigating larger sample sizes are required for conclusive findings.
Keyphrases
- risk factors
- end stage renal disease
- chronic kidney disease
- left ventricular assist device
- systematic review
- peritoneal dialysis
- type diabetes
- blood pressure
- ejection fraction
- cardiovascular disease
- public health
- newly diagnosed
- case control
- prognostic factors
- mental health
- electronic health record
- meta analyses
- adipose tissue
- glycemic control
- skeletal muscle
- artificial intelligence
- double blind