The flavonoid compound apigenin prevents colonic inflammation and motor dysfunctions associated with high fat diet-induced obesity.

Daniela GentileMatteo FornaiRocchina ColucciCarolina PellegriniErika TirottaLaura BenvenutiCristina SegnaniChiara IppolitoEmiliano DurantiAgostino VirdisSara CarpiPaola NieriZoltán H NémethLaura PistelliNunzia BernardiniCorrado BlandizziLuca Antonioli

Published in: PloS one (2018)

Apigenin prevents systemic metabolic alterations, counteracts enteric inflammation and normalizes colonic dysmotility associated with obesity.

Keyphrases

high fat diet induced
insulin resistance
oxidative stress
metabolic syndrome
type diabetes
adipose tissue
mouse model
weight loss
skeletal muscle
physical activity
body mass index