Login / Signup

Long-term opioid therapy definitions and predictors: A systematic review.

Ruchir N KarmaliChristopher BushSudha R RamanCynthia I CampbellAsheley C SkinnerAndrew W Roberts
Published in: Pharmacoepidemiology and drug safety (2019)
Most LTOT definitions aligned with the chronic pain definition (pain more than 3 months), and used cumulative duration of opioid use as a criterion, although most did not account for consistent use. Definitions were varied and rarely accounted for prescription characteristics, such as days' supply. Predictors of LTOT were similar to known risk factors of opioid abuse, misuse, and overdose. As LTOT becomes a central component of quality improvement efforts, researchers should incorporate criteria to identify consistent opioid use to build the evidence for safe and appropriate use of prescription opioids.
Keyphrases
  • chronic pain
  • quality improvement
  • pain management
  • risk factors
  • patient safety
  • bone marrow