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Phenotypic drift in metastatic progression of breast cancer: A case report with histologically heterogeneous lesions that are clonally related.

Jamie R KutasovicAmy E McCart ReedAnna SokolovaJanani JayanthanLeonard Da SilvaPeter Thomas SimpsonSunil R Lakhani
Published in: Clinical case reports (2020)
Breast cancer metastasis to the stomach is rare; invasive lobular carcinoma has a predilection to spread to the gastrointestinal system and is morphologically similar to primary diffuse gastric carcinoma. This case highlights heterogeneous metastatic progression and that documentation of heterogeneity is important for informing future treatment strategies and prognostication.
Keyphrases
  • squamous cell carcinoma
  • small cell lung cancer
  • single cell
  • low grade
  • young adults
  • advance care planning
  • childhood cancer