Comprehensive integrative profiling of upper tract urothelial carcinomas.

Xiaoping SuXiaofan LuSehrish Khan BazaiEva CompératRoger MouawadHui YaoMorgan RouprêtJean-Philippe SpanoDavid KhayatIrwin DavidsonNizar N TannirFangrong YanGabriel G Malouf

Published in: Genome biology (2021)

Our study delineates for the first time the key role for convergence between genetic and epigenetic alterations in shaping clinicopathological and immune upper tract urothelial carcinoma features.

Keyphrases

high grade
dna methylation
gene expression
single cell
network analysis