Sodium-glucose cotransporter 2 (SGLT2) inhibitors and fracture risk in patients with type 2 diabetes mellitus: A meta-analysis.

Darin RuanpengPatompong UngprasertJutarat SangtianTasma Harindhanavudhi

Published in: Diabetes/metabolism research and reviews (2017)

Increased risk of bone fracture among patients with type 2 diabetes mellitus treated with SGLT2 inhibitors compared with placebo was not observed in this meta-analysis. However, the results were limited by short duration of treatment/follow-up and low incidence of the event of interest.

Keyphrases

systematic review
risk factors
hip fracture
meta analyses
bone mineral density
glycemic control
clinical trial
cardiovascular risk factors
metabolic syndrome
bone loss
adipose tissue
skeletal muscle
newly diagnosed
weight loss
phase iii