Atypical imaging presentation of herpes simplex virus encephalitis in paediatric immunocompromised oncology patients.
Tejas H KapadiaArpita Sahu AAnurag GuptaChetan DhamneMaya PrasadGirish ChinaswamySeema KembhaviPublished in: Journal of medical imaging and radiation oncology (2021)
Immunocompromised paediatric patients with haematological malignancies have widespread atypical brain involvement in herpes simplex encephalitis with lack of diffusion restriction and post-contrast enhancement, likely due to haematogenous spread of HSV across the blood-brain barrier, lack of cellular immunity and limited inflammatory cytokine response.
Keyphrases
- herpes simplex virus
- end stage renal disease
- intensive care unit
- emergency department
- ejection fraction
- chronic kidney disease
- newly diagnosed
- high resolution
- magnetic resonance
- oxidative stress
- prognostic factors
- peritoneal dialysis
- white matter
- computed tomography
- patient reported outcomes
- resting state
- multiple sclerosis
- fluorescence imaging