Role of peripheral sensory neuron mu-opioid receptors in nociceptive, inflammatory, and neuropathic pain.

Awinita BarpujariNeil FordShao-Qiu HeQian HuangClaire Gaveriaux-RuffXinzhong DongYun Guan

Published in: Regional anesthesia and pain medicine (2020)

MOPs in primary sensory neurons contribute to the modulation of neuropathic pain behavior and opioid analgesia. Our observations highlight the clinical potential of peripherally acting opioid agonists in the management of inflammatory and neuropathic pain.

Keyphrases

neuropathic pain
pain management
spinal cord
chronic pain
spinal cord injury
oxidative stress
climate change