Possibility of avoiding axillary lymph node dissection by immune microenvironment monitoring in preoperative chemotherapy for breast cancer.
Koji TakadaShinichiro KashiwagiWataru GotoYuka AsanoKatsuyuki TakahashiHisakazu FujitaTsutomu TakashimaShuhei TomitaKosei HirakawaMasaichi OhiraPublished in: Journal of translational medicine (2018)
Even if macrometastases are found on SLNB in cN0 patients, it appears that ALND could be avoided after NAC in cases with a good immune tumor microenvironment of the primary tumor.
Keyphrases
- end stage renal disease
- lymph node
- ejection fraction
- newly diagnosed
- sentinel lymph node
- chronic kidney disease
- stem cells
- transcription factor
- patients undergoing
- prognostic factors
- peritoneal dialysis
- rectal cancer
- neoadjuvant chemotherapy
- prostate cancer
- squamous cell carcinoma
- locally advanced
- patient reported outcomes