Respiratory magnetic resonance imaging biomarkers in Duchenne muscular dystrophy.
Ami MankodiWilliam KovacsGina NoratoNathan HsiehW Patricia BandettiniCourtney A BishopHirity ShimellisRexford D NewbouldEunhee KimKenneth H FischbeckAndrew E AraiJianhua YaoPublished in: Annals of clinical and translational neurology (2017)
Cine breathing MRI allows independent and reliable assessment of the diaphragm and chest wall dynamics during the breathing cycle in DMD patients and controls. The MRI data indicate that ambulatory DMD patients breathe at lower lung volumes than controls when their FVC is in the normal range. The diaphragm moves normally, whereas chest wall motion is reduced in these boys with DMD.
Keyphrases
- duchenne muscular dystrophy
- magnetic resonance imaging
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- contrast enhanced
- peritoneal dialysis
- muscular dystrophy
- magnetic resonance
- mass spectrometry
- machine learning
- electronic health record
- big data
- deep learning
- extracorporeal membrane oxygenation