Association of cognitive reserve with the risk of dementia in the UK Biobank: role of polygenic factors.

Wenzhe YangJiao WangAbigail DoveMichelle M DunkXiuying QiDavid A BennettWei-Li Xu

Published in: The British journal of psychiatry : the journal of mental science (2024)

High cognitive reserve is associated with reduced risk of dementia and may delay dementia onset. Genetic risk for dementia may be mitigated by high cognitive reserve. Our findings underscore the importance of enhancing cognitive reserve in dementia prevention.

Keyphrases

mild cognitive impairment
cognitive impairment
genome wide
dna methylation
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