Reduced exercise capacity, chronotropic incompetence, and early systemic inflammation in cardiopulmonary phenotype Long COVID.
Matthew S DurstenfeldMichael J PelusoPunita KavetiChristopher HillDanny LiErica SanderShreya SwaminathanVictor M ArechigaScott LuSarah A GoldbergRebecca HohAhmed ChennaBrandon C YeeJohn W WinslowChristos J PetropoulosJ Daniel KellyDavid V GliddenTimothy J HenrichJeffrey N MartinYoo Jin LeeMandar A ArasCarlin S LongDonald J GrandisSteven G DeeksPriscilla Y HsuePublished in: The Journal of infectious diseases (2023)
Cardiopulmonary symptoms >1 year following COVID-19 were associated with reduced exercise capacity, which was associated with elevated inflammatory markers early in PASC. Chronotropic incompetence may explain exercise intolerance among some with cardiopulmonary Long COVID.