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RNA-binding protein LSM7 facilitates breast cancer metastasis through mediating alternative splicing of CD44.

Chenxin LiYuhao ZhangYun WangJing OuyangYingqian YangQingqing ZhuYingsi LuTingting KangYan LiMing XiaJinrun ChenQiji LiChengming ZhuLiping Ye
Published in: Life sciences (2024)
In summary, this study highlights the pivotal role of LSM7 in the production of the CD44s isoform and the promotion of breast cancer metastasis. Targeting the TCF3/LSM7/CD44s axis may offer a promising therapeutic strategy for breast cancer treatment.
Keyphrases
  • binding protein
  • nk cells
  • cancer therapy
  • drug delivery