Primary Oro-Facial Manifestations of Langerhans Cell Histiocytosis in Pediatric Age: A Bi-Institutional Retrospective Study on 45 Cases.

Saverio Capodiferro Angela Tempesta Luisa Limongelli Giuseppe Ingravallo Eugenio MaioranoGian Luca SfasciottiMaurizio BossùAntonella PolimeniGianfranco Favia

Published in: Children (Basel, Switzerland) (2020)

Langerhans Cell Histiocytosis may mimic several oro-facial inflammatory and neoplastic diseases. Considering the potential disabling sequela following head and neck localization of Langerhans Cell Histiocytosis in children, especially at the periodontal tissues with teeth and alveolar bone loss, lesion recognition along with the histological examination of suspicious tissues is mandatory to achieve an early diagnosis and to prevent further organ involvement.

Keyphrases

single cell
cell therapy
gene expression
bone loss
stem cells
young adults
risk assessment
climate change
bone marrow